2 min read

Free Webinar: Accelerating the antibody discovery workflow in the modern therapeutic landscape

By Ryan Kelly on 4/9/20 9:15 AM

How can we access greater antibody diversity through the plasma B cell repertoire? How can we down-select lead candidates in 1 day? Join Abveris and Berkeley Lights for an exclusive webinar opportunity to learn how we're redefining the boundaries of antibody discovery with the Berkeley Lights Beacon platform.

Tuesday, April 14, 2020, 11 am EDT

View on-demand Webinar
 
Overview:

As the complexity of therapeutic targets continues to evolve, more efficient and predictive identification of pertinent antibody candidates becomes increasingly valuable. Incorporating state-of-the-art, high-resolution discovery and characterization tools like the Berkeley Lights platform into discovery workflows enables rapid and reliable selection of lead candidates more effectively than traditional techniques. Elucidating function early during screening and development can enhance candidate triage, as opposed to relying on brute-force methods to characterize large panels containing primarily non-functional clones. Optimization of the discovery platform using the Beacon instrument and case studies will be outlined.

Speakers:
Colby A. Souders, Ph.D., Chief Scientific Officer, Abveris

Colby holds a PhD in Cell and Molecular Biology from Texas A&M and has spent the last decade focused on antibody research. He first joined MassBiologics to lead discovery programs, develop platform technologies and advance monoclonal antibodies in the pipeline for the prevention, treatment or diagnosis of infectious and endogenous diseases. He later joined the Kanyos Bio Protein Engineering team to develop therapeutics based on a novel antigen-specific immune tolerance platform. In 2018 Colby joined Abveris Antibody with the goal as Chief Scientific Officer to usher in new antibody discovery tools and build a premium discovery engine.

Anupam Singhal, Ph.D., Product Manager, Antibody Therapeutics, Berkeley Lights

Anupam Singhal earned his PhD from the University of British Columbia and has over 15 years of experience in nanotechnology and microfluidics at UBC, the University of Toronto and Stanford University. His work has been cited over 600 times and resulted in several patents for molecular disease diagnosis, antibody discovery, and development of production cell-lines for biologics. At Berkeley Lights, Anupam leads the development of next-generation platforms for the discovery and development of antibody therapeutics.

View on-demand Webinar

Topics: Insider Service & Product Updates Events
2 min read

Abveris and ACROBiosystems extend partnership

By Travis LeGuyader on 4/8/20 7:00 AM

Canton, MA, USA and Newark, DE, USA, April 8, 2020 - Abveris, Inc., a leader in contract research antibody discovery, today announced the extension of a strategic collaboration with ACROBiosystems, an internationally recognized manufacturer of recombinant proteins.

Under the terms of the agreement, the companies will leverage their core technologies to construct streamlined offerings to accelerate the pace of antibody discovery research.

Acro LogoBy the terms of the agreement, over 1600 recombinant proteins for biologic drug discovery and development available in the ACROBiosystems catalog will be made available to Abveris customers to facilitate rapid initiation of antibody discovery projects.

1600+ reagents at your fingertips click here to view the acro catalog

"Our collaboration with ACROBiosystems is a highly valuable resource for Abveris and all of our partner companies,” commented Ryan Kelly, Director of Business Development at Abveris. "Our access to ACRO’s high-quality “off-the-shelf” reagents allows us to identify diverse, high affinity antibody clones in as little as one month total.”

“We are delighted to collaborate with Abveris, who shows their expertise in therapeutic antibody development. Their special DiversimAbTM platform and single B cell screening platform speed up the antibody generation process while providing maximum diversity and affinity of the antibody candidates. It delivers additional benefits and comforts to scientists with using ACRO’s high-quality reagents and Abveris’s technologies as a combination,” commented Simin He, Marketing Manager of ACROBiosystems.

LET'S GET STARTED ON YOUR ANTIBODY PROJECT CLICK HERE TO INSTANTLY SET UP A CALL.

About Abveris: 

Abveris is a Boston-area specialty antibody discovery contract research organization located in Canton, Massachusetts, USA. Abveris partners with large and small biopharmaceutical companies to discover novel therapeutic products and critical reagent antibodies using diverse platforms, including the proprietary DiversimAb™ hyperimmune mouse technology. Additional information about Abveris is available at www.abveris.com.

About ACROBiosystems: 

ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application-oriented development strategy, with a particular focus on product design, quality control and solution-based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. Check out more details at: www.acrobiosystems.com/.

Contact for Abveris:

Ryan Kelly

Director of Business Development

rkelly@abveris.com

781-562-1170 x1002

Contact for ACROBiosystems:

Grace Wang

Marketing Specialist

Grace.wang@acrobiosystems.com

408-320-2195

 

Topics: Insider Service & Product Updates
1 min read

Staying Open for Science, COVID Response

By Ryan Kelly on 3/20/20 12:44 PM

Abveris, Inc. 

March 18, 2020
RE: Staying Open for Science, COVID Response

 

To Our Valued Customers & Partners,

The COVID outbreak has caused significant disruptions to the science community worldwide, and your ongoing antibody discovery projects shouldn’t cause additional stress. Abveris will remain open for business and continue to provide contract research services during the state of emergency even if a "shelter-in-place" order is called. 

Abveris has multiple ongoing projects that directly contribute to drug development efforts for underserved diseases and indications (including COVID-19 and multiple other viral agents). Our end-to-end antibody discovery services are fully operational and we’re accepting new hybridoma and B cell screening discovery projects. Are you delaying your discovery work because of COVID-related antigen production delays? We can help.

Schedule 15 minutes with us today to discuss your project.

We are closely monitoring communications from the Massachusetts State and Federal Governments regarding measures to prevent the spread of the virus. Abveris has implemented mandatory work-from-home policies for non-essential staff, and employee schedules have been adjusted to promote social distancing. 

We welcome you to lean on us during these turbulent times. As always, we look forward to supporting your science.

 

Sincerely,

Garren Hilow

CEO of Abveris

 

Adversity has the effect of eliciting talents,

which in prosperous circumstances would have lain dormant

- Horace

Topics: Insider Press Releases Service & Product Updates
1 min read

Hey, Boston & Cambridge!  We're hosting a free happy hour!

By Travis LeGuyader on 2/12/20 7:30 AM

Updated 3/6/20: Event cancelled due to concerns surrounding spread of COVID-19 virus. 
A note from the event organizers:
Thank you for your interest in our event, and we apologize that we must postpone the happy hour indefinitely due to concerns surrounding the spread of Covid-19 infection. 
We're proud to announce that we had over 100 attendees registered a week ahead of the event. When the time is right, we will announce a revised event date. 

Thursday | March 12 | 5:00-7:30 PM | Cambridge, MA

Open Bar & Free Appetizers

What is Brews & Biopharma?

A free happy hour for biopharma scientists.

An exclusive, relaxed event for biopharma scientists in the protein sciences. Finish your workday (and start your night) with us over casual drinks, appetizers, and networking.

Who is invited?

Scientists from our partner companies and their invited guests*

*We kindly ask you not to invite your professional recruiter or salesperson friends as your guests. Nobody likes to be pitched after work. Thank you for respecting our policy. 

Topics: Insider Events
1 min read

Sustainable Science: Introduction to Our Green Initiatives Blog

By Matthew Bartolucci on 2/7/20 7:30 AM

 
Abveris is excited to announce our new Green Initiatives blog series.
Why are we “green-ing” our operations?


We are a group of biopharmaceutical scientists advancing a scientific mission to produce better biotherapeutic drugs. While our mission does not directly relate to environmental science, we recognize that environmental health ties directly to human health. Global climate scientists have reached a clear consensus: to address climate change, dramatic action must be taken now. To ignore our company’s contribution to global carbon emissions and climate change is irresponsible.

What’s the plan?

Abveris is enacting sweeping changes to our laboratory and business operations to reduce our company's carbon footprint. Did you know that laboratory facilities use 5-10x more energy compared to similarly-sized “normal” office spaces? As our lab continues to grow, we're scrutinizing our policies on energy use and sustainability so we can build valuable therapeutic products without leaving a harmful footprint.

Why are we blogging about it?

In this blog series, you’ll find information about our efforts to overhaul our company operations and move towards net carbon-neutrality. These initiatives extend beyond our laboratory and office to build support for eco-conscious behaviors at work, at home, and in our supply chain. By showcasing what we are doing in our labs and offices, we hope that other pharmaceutical scientists can follow our progress and enact changes in their own companies and institutions.

In each of our posts, we’ll break down the following:
  • What specific action are we taking to address climate change?
  • Why are we making a change?
  • What's the implementation strategy?
  • How do we expect to make an impact?
  • How can you, the reader, make a similar change in your own company?

Check out this blog series at abveris.com/greenscience to stay updated on our progress!

Topics: Green Initiatives
1 min read

WEBINAR: Integrating Octet into Early Antibody Discovery Workflows

By Ryan Kelly on 1/8/20 3:14 PM

Date: January 29, 2019 at 10AM ET (7AM PT)

Please join FortéBio and Abveris for an exclusive webinar featuring Colby Souders, Chief Scientific Officer of Abveris, who will review ways to utilize Octet screening to streamline antibody discovery projects.

View on demand Webinar

 

Who should attend:
  • Antibody discovery scientists and researchers engaged in therapeutic drug discovery.
  • Anyone interested in learning more about leveraging high-throughput Octet screening analyses to advance research and development.

Overview:

Integrating Octet into Early Antibody Discovery Workflows

Colby Souders, Chief Scientific Officer, Abveris

As industry-wide advancements in antibody drug discovery continue to push toward larger panels of candidates for early-stage characterization, more efficient identification of lead molecules through enhanced screening resolution is required. Integrating instruments like the Octet into the overall characterization workflow enables reliable, high throughput selection of lead candidates more effectively than alternative traditional techniques. This presentation will highlight a few unique methods of Octet utilization as a replacement or supplemental tool for various antibody discovery protocols. Comparisons across platforms, including traditional ELISA, flow cytometry, SPR, and in vivo studies will be presented.

 

View on demand Webinar

Topics: Insider
1 min read

COO of Abveris, Tracey Mullen, to Present at Antibody Engineering 2019 in San Diego

By Travis LeGuyader on 12/3/19 1:49 PM

December 9, 2019 – San Diego, CA - Are you attending the upcoming Antibody Engineering and Therapeutics conference in San Diego on December 9th? It’s not too late to sign up and spend some time in the sun while staying updated on the latest antibody discovery technologies and engineering techniques while networking with lead scientists in the antibody discovery world.

Join us on December 12 at noon for a scientific briefing led by Tracey Mullen, our Chief Operating Officer. Or, stop by our booth or posters in the exhibit hall and meet with Garren (CEO), Ryan (Director of Business Development) and Travis (Business Development Associate). See you there!

Click here to schedule an appointment with our team at the conference.

 

Information on our Scientific Briefing:
Scientific Briefing: Antibody Discovery for Traditionally Difficult Targets: in vivo, in vitro, or both?

Abstract: Leveraging the natural immune repertoire for antibody discovery has distinct advantages for positive downstream outcomes, including efficacy, developability and safety; however, traditional techniques typically fail to produce a productive response in situations where, for example, the target epitope has poor immunogenicity or is a rare, cryptic site. While some in vitro platforms can overcome these difficulties through careful guiding selection methods, significant downstream engineering is often required to ensure lead candidates harbor appropriate development qualities. Fortunately, recent advancements in protein engineering and antibody discovery have enabled improved drug development to these traditionally difficult targets. Using the AbX platform, the power of the immune system is harnessed to exemplify the breadth and comprehensive nature of the B cell repertoire. When applied to the most difficult target classes, lead candidates can be uncovered where traditional in vivo platforms typically fail, or significant engineering is required for in vitro discovery.

About the Antibody Engineering Conference: Antibody Engineering is the #1 antibody engineering conference for accelerating next-generation antibodies to commercial success. Find the latest science, technology, and partners in antibody engineering, immunobiology, and next-generation binders.

 

Antibody Engineering Logo

 

Topics: Conferences
1 min read

Streamlining I-O Therapeutic Antibody Discovery: An Interview with Tracey Mullen, COO of Abveris

By Ryan Kelly on 12/3/19 7:34 AM

Insights from industry: Tracey Mullen, Chief Operating Officer of Abveris

Visit News Medical today to view an interview with Tracey Mullen, Chief Operating Officer of Abveris, in the "Insights from Industry" interview series.

In the interview, Tracey gives an overview of immuno-oncology therapeutic antibodies in development, strategies for therapeutic antibody discovery, and applications for the Intellicyt iQue high-throughput flow cytometry platform in antibody discovery.

For more information on antibody discovery projects utilizing high-throughput flow cytometry, contact Abveris today!

VIEW THE INTERVIEW

1 min read

WEBINAR: High-Throughput Antibody Discovery Targeting Glycoproteins for Apoptosis Induction in Cancer

By Ryan Kelly on 11/12/19 8:15 AM

Date: December 4, 2019 at 11AM ET (8AM PT)

IMG_1616Please join Sartorius and Abveris for an exclusive webinar featuring Tracey Mullen, Chief Operating Officer of Abveris, who will review an antibody discovery campaign targeting a glycoprotein for induction of apoptosis. Methods for immunization, screening for lead antibody candidates and subsequent functional characterization through the use of the Intellicyt® iQue platform will be detailed.

Who should attend:
  • Antibody discovery scientists and researchers engaged in therapeutic drug discovery for oncology indications.
  • Anyone interested in learning more about leveraging high-throughput flow cytometry analysis to advance research and development.
Interested, but have a scheduling conflict? Click here to register and receive an on-demand link to watch later.
About the webinar:

The use of monoclonal antibody-based drugs has proven very successful to target and treat cancer with more than half of late-stage clinical trial antibodies carrying an oncology indication. By employing multiple final formats, unconjugated or conjugated antibodies capitalize on methods of cell killing spanning from direct targeting and inhibition of cell survival pathways to shuttling and delivery of cytotoxic drugs. Specific cell surface antigen recognition is paramount to the success of these drugs, necessitating high resolution early stage characterization of lead antibody drug candidates prior to preclinical development.

Major advancements in high-throughput flow cytometry have enabled more exquisite antibody discovery within the oncology field by providing thorough analysis of on-cell antigen specificity and function earlier in the drug discovery process. In this webinar, an antibody discovery campaign targeting a glycoprotein for induction of apoptosis will be reviewed. Methods for immunization, screening for lead antibody candidates and subsequent functional characterization through the use of the Intellicyt iQue platform will be detailed.

Topics: Insider Service & Product Updates
1 min read

WEBINAR: Excellence In Anti-Idiotype Antibody Discovery

By Travis LeGuyader on 10/28/19 6:29 PM

Date: November 13, 2019 at 2PM ET (11AM PT)
TraceyMullenPlease join Abveris' Chief Operating Officer, Tracey Mullen, for our webinar to learn more about our premier anti-idiotype antibody discovery service for mAbs, bispecifics, scFvs, VHHs, and more.

Benefits of our approach:
  • Rapid reagent generation timelines
  • Maximal epitope coverage with DiversimAb technology
  • Highly sensitive specificity screening
  • Identification of high-affinity mAbs
  • Neutralizing and non-neutralizing mAbs
  • Flexible deliverable strategies
  • All work done in the USA

Abveris has the expertise and technology advantages required to develop high-quality reagents to the trickiest biotherapeutic molecules. Join our webinar to learn more.
Interested, but have a scheduling conflict? Click here to register and a video link will be sent after the webinar finishes. 
Topics: Insider Service & Product Updates

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