The Beacon platform by Berkeley Lights is a disruptive, best-in-industry technology for single B-cell screening. It enables high resolution screening of antibody secreting B-cells with a throughput and timeline that was unimaginable just a few years ago. Days after tissue collection, the Beacon provides a rich data set about each antibody screened to identify the rare, active, cross-reactive mAbs that are ideal for clinical development. Those antibodies are then sequenced and expressed rapidly to advance them to downstream assays.
The Beacon platform is a perfect combination with our ability to generate immune responses in-vivo against difficult-to-target epitopes and our expertise in downstream characterization.
By screening mAbs in for the proper functional activity and cross-reactivity upfront the process is much more efficient than the age-old method of developing and expressing thousands of mAbs to identify the few with relevant function. This results in better mAbs, delivered faster and with less wasted resources.
We like to meet in person with our Boston clients. We can setup a Zoom to connect if you're further away.