Twist Bioscience Opens New Twist Boston Location
SOUTH SAN FRANCISCO, Calif. – July 6, 2022 – Twist Bioscience Corporation (NASDAQ: TWST), a...
affinity (apparent KD)
With our iQue Screener PLUS flow cytometer we screen antibodies for on-cell binding to identify massive panels of antigen-specific antibodies for further interrogation.
The iQue achieves faster assay throughput than traditional flow cytometers by sampling only microliters from each well and delivering an air-gap-delimited flow of samples to the detectors.
The iQue Screener PLUS converts the traditional low throughput, time-consuming flow cytometry approach into a high throughput process.
The end result is a data-rich snapshot of the molecular events occurring in each well that can take less than five minutes for a 96-well plate.
Real time label-free binding analyses have introduced a new era in antibody screening and characterization, quickly. Abveris employs Carterra Surface Plasmon Resonance (SPR) and Octet Bio-Layer Interferometry (BLI) for detection of label-free molecular interactions.
Carterra SPR and Octet BLI are fully integrated into our custom monoclonal antibody development so that we can screen hundreds of monoclonal antibody candidates for desired binding specificity and kinetics suited for your intended application(s).
Both the Carterra and Octet based analyses are stand-alone services available to partners interested in binding kinetic analyses.
Species Cross-Reactivity Assessments
Kinetics, Affinity, KD determination
Epitope Binning, Antibody Pairing
Ligand Blocking Analyses
Rapid Antibody Quantitation
Enzyme-Linked Immunosorbent Assays (ELISAs) are one of the most common and transferrable screening formats employed for antibody-based assays.
ELISA-type assays are especially beneficial for soluble or secreted targets. In particular, they’re useful for the development of critical reagents or PK or ADA assays to support clinical development or for the discovery and characterization of antibodies against soluble therapeutic targets.
- High-throughput, highly automated platform
- Experience with diverse assay formats, including indirect ELISA, capture ELISA, bridging ELISA, competition ELISA, and more.