Ryan Kelly

Ryan Kelly

Associate Director of Business Development @ Abveris

Recent posts by Ryan Kelly

3 min read

Abveris beer: Get It While It's cold!

By Ryan Kelly on 6/30/20 8:59 AM

Made by mAb scientists, for mAb scientists
BEST ENJOYED AFTER A LONG DAY IN THE LAB

We teamed up with our neighbors at Castle Island Brewery to bring you specialty beers that mAb scientists are sure to love! Introducing mAb Scientist IPA and Six Pack mAbs Lager. Our team designed some hilarious labels and the Castle Island team came through with some delicious lager and IPA options. 

We'll be sending out cases of beer to our partners, but we also recognize many of you are working from home right now. Click below to provide your address information for us to send you some free brews! 

BEER CALL: ADD ME TO THE LIST!

mAb Scientist IPA: OUR FLAGSHIP BEER
Abveris Beer Labels FINAL 2020-04-072 mab scientist

This beer is smooth but punchy; balanced yet intense. Despite the colossal amount of hops crammed into this beer, it’s still remarkably approachable for pros and rookies alike!

Our team held a naming competition for our flagship beer. After a close vote with many great names in the running, mAbScientist IPA rose to victory.  You may be asking: why does she have antibodies for hands? Fun fact: our monthly all-hands meeting is called "Monthly mAbs For Hands" after our all hands on approach to antibody discovery. 

MALTS: 2 ROW, VIENNA, CRYSTAL DEXTROSE

HOPS: SIMCOE, CASCADE

YEAST: HOUSE YEAST

Six Pack mAbs Lager: A SUMMER SPECIAL
Abveris Beer Labels FINAL 2020-04-07 six pack mabs

Whether you’re catching the game, conquering the trail, or walking in the door from your commute home, sometimes you just need a beer. Brewed distinctively for the everyday, this classic American Lager is light and crisp, and will have you reaching for another sip. So kick your feet up, breathe easy, and crack into a can of this liquid bliss."

This beer label speaks for itself. We all love the beach this time of the year, and we love showing off the muscles we've built while sitting on our butts all day at the biosafety cabinets. 

MALTS: PILSNER, BOHEMIAN WHEAT

HOPS: MAGNUM, RAKAU

YEAST: LAGER YEAST

About Abveris: 

Abveris is Boston's premier antibody discovery company providing contract research services to the biopharma industry. Abveris applies advanced immunization methods combined with B cell screening and hybridoma-based antibody discovery technologies to provide comprehensive gene-to-antibody discovery services. Abveris is developing the next generation of biologics, cell therapies, vaccines, and diagnostics in partnership with global leaders in biopharma. Additional information about Abveris is available at www.ABVERIS.com.

About Castle Island Brewery: 

Castle Island Brewery is based out of Norwood, Ma and can be found in fridges across New England. Their tasteful, easy to drink selection of beers is perfect for all beer drinkers from the beginner to the beer expert. Castle Island has their main staples, including the Keeper, American Lager, White Ale and CandlePin but they are always making new exciting beers to keep up with their loyal customers evolving tastes! Check out more on their website: www.castleislandbeer.com

Topics: Insider Events
2 min read

Abveris Announces Partnership with Nkarta using the Trianni Mouse on the Berkeley Lights Beacon

By Ryan Kelly on 5/12/20 8:08 AM

Click here to see the press release on BusinessWire.

Canton, MA, USA – Abveris, Inc. (“Abveris”) announced today that it has entered into an antibody discovery partnership with Nkarta, Inc. (“Nkarta”) for the discovery of fully-human monoclonal antibodies to support the advancement of Nkarta’s novel cell-based therapeutics. Under the terms of the agreement, Abveris will apply its next-generation B cell screening platform (powered by the Berkeley Lights Beacon®) to rapidly discover fully human monoclonal antibodies using the Trianni Mouse®, an industry-leading transgenic mouse R&D platform. 

“We have worked with the Trianni Mouse across several therapeutic antibody programs and have been impressed with the success of these campaigns,” commented Colby Souders, Ph.D., Chief Scientific Officer of Abveris. “Abveris is uniquely positioned to dramatically shorten therapeutic discovery timelines while enhancing candidate selection by pairing optimized immunization methods in the Trianni Mouse with high-resolution single B cell screening enabled by the Berkeley Lights Beacon.”    

Trianni

“We believe this partnership brings together powerful discovery technologies with the potential for accelerating Nkarta’s pipeline of natural killer cell therapy candidates,” said James Trager, Ph.D., Chief Scientific Officer of Nkarta. “We look forward to working closely with the Abveris team on the identification of targeted antibodies ideally suited for our cell engineering and manufacturing platform.”

Learn more:  B cell screening at Abveris

“The Nkarta team is situated to redefine the way we think about cell therapies, and we are delighted to be working with their team of impassioned scientists,” added Tracey Mullen, MBA, Chief Operating Officer of Abveris. “This partnership highlights our continued commitment to working with organizations leveraging antibody therapeutics in innovative and transformative ways.” 

"We at Trianni are thrilled that the partnership of Abveris and Nkarta includes the use of the Trianni Mice. It is gratifying to contribute to the program of creating novel antibody therapeutics," said Matthias Wabl, Ph.D., Chief Executive Officer of Trianni, Inc.

Get in touch with Abveris

About Abveris: 

Abveris is Boston's premier antibody discovery company providing contract research services to the biopharma industry. Abveris applies advanced immunization methods combined with B cell screening and hybridoma-based antibody discovery technologies to provide comprehensive gene-to-antibody discovery services. Abveris is developing the next generation of biologics, cell therapies, vaccines, and diagnostics in partnership with global leaders in biopharma. Additional information about Abveris is available at www.ABVERIS.com.

About Trianni, Inc: 

Trianni, Inc. is a privately held biotech company specializing in antibody discovery technology. Trianni’s lead technology, the Trianni Mouse®, is a powerful, next-generation platform enabling efficient generation of fully-human monoclonal antibodies. Trianni’s transgenic platform leverages a novel approach to design made possible by advances in DNA synthesis and genomic modification technology. The company is headquartered in San Francisco, CA. Additional information about Trianni is available through its corporate website, www.TRIANNI.com.

 

Contact for Abveris:

Ryan Kelly

Director of Business Development

rkelly@abveris.com

781-562-1170 x1002

 

Contact for Trianni:

Elizabeth Tran

Marketing manager

elizabeth.tran@trianni.com

(415) 231-0257

 

Topics: Insider Press Releases
2 min read

Free Webinar: Accelerating the antibody discovery workflow in the modern therapeutic landscape

By Ryan Kelly on 4/9/20 9:15 AM

How can we access greater antibody diversity through the plasma B cell repertoire? How can we down-select lead candidates in 1 day? Join Abveris and Berkeley Lights for an exclusive webinar opportunity to learn how we're redefining the boundaries of antibody discovery with the Berkeley Lights Beacon platform.

Tuesday, April 14, 2020, 11 am EDT

View on-demand Webinar
 
Overview:

As the complexity of therapeutic targets continues to evolve, more efficient and predictive identification of pertinent antibody candidates becomes increasingly valuable. Incorporating state-of-the-art, high-resolution discovery and characterization tools like the Berkeley Lights platform into discovery workflows enables rapid and reliable selection of lead candidates more effectively than traditional techniques. Elucidating function early during screening and development can enhance candidate triage, as opposed to relying on brute-force methods to characterize large panels containing primarily non-functional clones. Optimization of the discovery platform using the Beacon instrument and case studies will be outlined.

Speakers:
Colby A. Souders, Ph.D., Chief Scientific Officer, Abveris

Colby holds a PhD in Cell and Molecular Biology from Texas A&M and has spent the last decade focused on antibody research. He first joined MassBiologics to lead discovery programs, develop platform technologies and advance monoclonal antibodies in the pipeline for the prevention, treatment or diagnosis of infectious and endogenous diseases. He later joined the Kanyos Bio Protein Engineering team to develop therapeutics based on a novel antigen-specific immune tolerance platform. In 2018 Colby joined Abveris Antibody with the goal as Chief Scientific Officer to usher in new antibody discovery tools and build a premium discovery engine.

Anupam Singhal, Ph.D., Product Manager, Antibody Therapeutics, Berkeley Lights

Anupam Singhal earned his PhD from the University of British Columbia and has over 15 years of experience in nanotechnology and microfluidics at UBC, the University of Toronto and Stanford University. His work has been cited over 600 times and resulted in several patents for molecular disease diagnosis, antibody discovery, and development of production cell-lines for biologics. At Berkeley Lights, Anupam leads the development of next-generation platforms for the discovery and development of antibody therapeutics.

View on-demand Webinar

Topics: Insider Service & Product Updates Events
1 min read

Staying Open for Science, COVID Response

By Ryan Kelly on 3/20/20 12:44 PM

Abveris, Inc. 

March 18, 2020
RE: Staying Open for Science, COVID Response

 

To Our Valued Customers & Partners,

The COVID outbreak has caused significant disruptions to the science community worldwide, and your ongoing antibody discovery projects shouldn’t cause additional stress. Abveris will remain open for business and continue to provide contract research services during the state of emergency even if a "shelter-in-place" order is called. 

Abveris has multiple ongoing projects that directly contribute to drug development efforts for underserved diseases and indications (including COVID-19 and multiple other viral agents). Our end-to-end antibody discovery services are fully operational and we’re accepting new hybridoma and B cell screening discovery projects. Are you delaying your discovery work because of COVID-related antigen production delays? We can help.

Schedule 15 minutes with us today to discuss your project.

We are closely monitoring communications from the Massachusetts State and Federal Governments regarding measures to prevent the spread of the virus. Abveris has implemented mandatory work-from-home policies for non-essential staff, and employee schedules have been adjusted to promote social distancing. 

We welcome you to lean on us during these turbulent times. As always, we look forward to supporting your science.

 

Sincerely,

Garren Hilow

CEO of Abveris

 

Adversity has the effect of eliciting talents,

which in prosperous circumstances would have lain dormant

- Horace

Topics: Insider Press Releases Service & Product Updates
1 min read

WEBINAR: Integrating Octet into Early Antibody Discovery Workflows

By Ryan Kelly on 1/8/20 3:14 PM

Date: January 29, 2019 at 10AM ET (7AM PT)

Please join FortéBio and Abveris for an exclusive webinar featuring Colby Souders, Chief Scientific Officer of Abveris, who will review ways to utilize Octet screening to streamline antibody discovery projects.

View on demand Webinar

 

Who should attend:
  • Antibody discovery scientists and researchers engaged in therapeutic drug discovery.
  • Anyone interested in learning more about leveraging high-throughput Octet screening analyses to advance research and development.

Overview:

Integrating Octet into Early Antibody Discovery Workflows

Colby Souders, Chief Scientific Officer, Abveris

As industry-wide advancements in antibody drug discovery continue to push toward larger panels of candidates for early-stage characterization, more efficient identification of lead molecules through enhanced screening resolution is required. Integrating instruments like the Octet into the overall characterization workflow enables reliable, high throughput selection of lead candidates more effectively than alternative traditional techniques. This presentation will highlight a few unique methods of Octet utilization as a replacement or supplemental tool for various antibody discovery protocols. Comparisons across platforms, including traditional ELISA, flow cytometry, SPR, and in vivo studies will be presented.

 

View on demand Webinar

Topics: Insider
1 min read

Streamlining I-O Therapeutic Antibody Discovery: An Interview with Tracey Mullen, COO of Abveris

By Ryan Kelly on 12/3/19 7:34 AM

Insights from industry: Tracey Mullen, Chief Operating Officer of Abveris

Visit News Medical today to view an interview with Tracey Mullen, Chief Operating Officer of Abveris, in the "Insights from Industry" interview series.

In the interview, Tracey gives an overview of immuno-oncology therapeutic antibodies in development, strategies for therapeutic antibody discovery, and applications for the Intellicyt iQue high-throughput flow cytometry platform in antibody discovery.

For more information on antibody discovery projects utilizing high-throughput flow cytometry, contact Abveris today!

VIEW THE INTERVIEW

1 min read

WEBINAR: High-Throughput Antibody Discovery Targeting Glycoproteins for Apoptosis Induction in Cancer

By Ryan Kelly on 11/12/19 8:15 AM

Date: December 4, 2019 at 11AM ET (8AM PT)

IMG_1616Please join Sartorius and Abveris for an exclusive webinar featuring Tracey Mullen, Chief Operating Officer of Abveris, who will review an antibody discovery campaign targeting a glycoprotein for induction of apoptosis. Methods for immunization, screening for lead antibody candidates and subsequent functional characterization through the use of the Intellicyt® iQue platform will be detailed.

Who should attend:
  • Antibody discovery scientists and researchers engaged in therapeutic drug discovery for oncology indications.
  • Anyone interested in learning more about leveraging high-throughput flow cytometry analysis to advance research and development.
Interested, but have a scheduling conflict? Click here to register and receive an on-demand link to watch later.
About the webinar:

The use of monoclonal antibody-based drugs has proven very successful to target and treat cancer with more than half of late-stage clinical trial antibodies carrying an oncology indication. By employing multiple final formats, unconjugated or conjugated antibodies capitalize on methods of cell killing spanning from direct targeting and inhibition of cell survival pathways to shuttling and delivery of cytotoxic drugs. Specific cell surface antigen recognition is paramount to the success of these drugs, necessitating high resolution early stage characterization of lead antibody drug candidates prior to preclinical development.

Major advancements in high-throughput flow cytometry have enabled more exquisite antibody discovery within the oncology field by providing thorough analysis of on-cell antigen specificity and function earlier in the drug discovery process. In this webinar, an antibody discovery campaign targeting a glycoprotein for induction of apoptosis will be reviewed. Methods for immunization, screening for lead antibody candidates and subsequent functional characterization through the use of the Intellicyt iQue platform will be detailed.

Topics: Insider Service & Product Updates

Now Hiring: Join Our Lab or Business Development Team

By Ryan Kelly on 10/19/19 1:59 PM

October 19, 2019 – Are you a team player looking for an exciting new challenge at a growing company? Visit our careers page today to learn about our open positions in our laboratory and business development teams.

Do you think you have the right attitude and the right experience to join our team, but the jobs we've posted don't look quite right for you? We welcome your application. Apply as an "antibody enthusiast" today!

Topics: Team Updates
1 min read

CSO of Abveris, Colby Souders, Ph.D., to Present at Discovery On Target 2019

By Ryan Kelly on 8/22/19 9:07 AM

August 22, 2019 – Boston, MA – Representatives from Abveris will attend the 17th Annual Discovery On Target Conference, September 16-19, 2019, in Boston, MA. Colby Souders, Chief Scientific Officer of Abveris, will serve as chairperson for the Antibody Engineering and Development Forum and present "Screening Tools for Early Prediction of Development and Clinical Success" at 3:40PM on Thursday, September 19. An abstract for the presentation is listed below.

Click here to schedule an appointment with the Abveris team during the conference.
Abstract:

As industry-wide advancements in antibody drug discovery continue to push toward larger panels of candidates for early-stage characterization, more efficient identification of lead molecules through enhanced screening resolution is required. Integrating tools and methods into the overall characterization workflow enables reliable, high throughput selection of lead candidates more effectively than alternative traditional techniques. Comparisons across platforms, including traditional ELISA, flow cytometry, Octet and in vivo studies will be presented that provide enhanced prediction of downstream development and clinical success.

About Discovery On Target:

The 17th Annual Discovery on Target (DOT), the industry’s preeminent event on novel drug targets and technologies, will convene over 1,300 drug discovery professionals in Boston, MA, on September 16-19, 2019. This event highlights advances in current and emerging “hot” targets and technologies, as well as target validation strategies for the discovery and development of novel therapeutic agents, ranging from biologics to small molecules.

Topics: Team Updates Conferences
3 min read

Meet the Team: Summer Interns

By Ryan Kelly on 7/9/19 10:30 AM

July 9, 2019 - Our team is comprised of creative, friendly, mission-focused antibody enthusiasts who take pride in discovery science. This summer, Abveris will be featuring all of our team members on our blog to showcase the personalities that make our team a community. Twice a week, tune in to learn more about members of our team and see what they do inside and outside of work.

 

Matthew Bartolucci - Business Development Intern

MattBartolocci

 

Q: What excites you about science?

A: Science allows for all our our greatest questions to be answered. With the world always changing and evolving, our science is the way that we are able to adapt as a society and prepare for the world ahead.

Q: What is your favorite fun fact?

A: Garren, our CEO, and I have both play/played college ultimate frisbee for Bentley University's Icehouse

Q: What do you do in your free time?

A: Hanging out with friends, playing ultimate frisbee, slow-pitch softball and basketball!

Q: What is the coolest thing you have done at Abveris or what is your favorite memory of working here?

A: I love the start-up culture! One minute, I am helping with our marketing tasks, and the next, I am helping others take out the garbage. Everyone pitches in and embraces the culture! 

 

Madeleine Carbonneau - Business Development Intern

 

MaddyCarbonneau

Q: What excites you about science?

A: There is still so much to discover! Every generation of scientists has the opportunity to make fantastic and revolutionary contributions.

Q: What is your favorite fun fact?

A: The national animal of Scotland is a unicorn.

Q: What do you do in your free time?

A: I like to run, drink coffee, and travel.

Q: What is the coolest thing you have done at Abveris or what is your favorite memory of working here?

A: The coolest thing I have done at Abveris is working on the back end of the website. It is really cool to see how different languages, programs, and software work together. Also, the people working at Abveris are all really great and committed to their work which makes working here all the more enjoyable.

 

Tadhg Daly - Lab Intern

 

TadhgDaley

Q: What excites you about science?

A: The pursuit of knowing more than I did yesterday

Q: What is your favorite fun fact?

A: Sloths can hold their breath longer than dolphins can.

Q: What do you do in your free time?

A: I like to collect retro video games and merchandise as well as play games with my friends.

Q: What is the coolest thing you have done at Abveris or what is your favorite memory of working here?

A: Assisting in protein purifications and being responsible for my own cell cultures for others to use in fusions

 

Kelly Rothenberger - Lab Intern

 

KellyRothenberger

Q: What excites you about science?

A: The possibility for discovering new concepts and that can help people in the future. Especially on the industry side, where creating exciting new things, (such as antibodies) can aid those who are using the new drug products to fight against different diseases. The exponential growth of the biotechnology industry is exciting and I cannot wait to see what I will be apart of in my future!

Q: What is your favorite fun fact?

A: When helium is cooled to almost absolute zero, it becomes a liquid, flowing against gravity and can start running up and over the lip of a glass container.

Q: What do you do in your free time?

A: I mostly enjoy to workout as often as I can, and I also horseback ride when possible.

Q: What is the coolest thing you have done at Abveris or what is your favorite memory of working here?

A: Watching my first fusion (done by Justin) on my 6th day of interning! I am so excited to make more memories!!

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